Ten-protein blood panel distinguishes ALS patients with near-98% accuracy

· Science · United States

Researchers at Emory University School of Medicine have identified 10 blood proteins that, analyzed together, distinguish people with amyotrophic lateral sclerosis (ALS) from healthy individuals with nearly 98% balanced accuracy. The findings, published in Nature Communications, suggest a blood test could eventually help diagnose the degenerative disease, which currently takes time to confirm. The panel reportedly outperformed the leading existing ALS biomarker in the study.

Why it matters：A reliable blood test for ALS would shorten a diagnosis that is often delayed and could speed enrollment in trials, a change that matters for neurology clinics and drug developers alike.

Key points

  • Emory researchers identified 10 blood proteins.
  • Balanced accuracy reached nearly 98%.
  • The findings appeared in Nature Communications.

Sources (original reporting)

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